Antioxidant effect via increased cellular antioxidant enzymes

Antioxidant effect via increased cellular antioxidant enzymes" refers to the enhanced neutralization of reactive oxygen species (ROS) achieved by boosting the activity or expression of a class of enzymes that protect cells from oxidative damage. Key enzymes include superoxide dismutases (SOD), catalase (CAT), glutathione peroxidases (GPx), and peroxiredoxins (Prx), which work together to scavenge ROS and maintain cellular redox balance. These enzymes play crucial roles in protecting against various diseases linked to oxidative stress, including cardiovascular and neurodegenerative diseases, cancer, and inflammatory conditions. Pharmacological and nutritional agents can enhance these pathways, and they are sometimes targeted for therapeutic or preventive interventions. The entry "Antioxidant effect via increased cellular antioxidant enzymes" is not a single gene, protein, or classical drug target; therefore, it should not be considered a canonical molecular target. It refers collectively to the actions of a set of enzymes and is a pathway/set, not a molecule.

Other names

Cellular antioxidant enzymesAntioxidant enzyme systemAntioxidant pathway

Induction or upregulation of endogenous enzyme expression; Direct enzyme activation; Protection against free radical damage via enzymatic scavenging