Antisense to TMEM5

"Antisense to TMEM5" (ENSG00000249753) is an annotated lncRNA gene transcribed antisense to the TMEM5 locus[2]. It does not code for a protein and has no established biological function, molecular classification, or pharmacological relevance as a therapeutic target. Its inclusion as a drug target is incorrect; it is not the functionally characterized TMEM5 protein (also known as RXYLT1), which is an enzyme implicated in muscular dystrophies and glycosylation disorders[1][5][7]. This lncRNA has no known role in disease, no interacting drugs, and no established mechanisms of action.\n\nKey distinction: If you are seeking a therapeutically relevant target, you likely want the protein-coding TMEM5 (Ribitol xylosyltransferase 1, RXYLT1), not the lncRNA antisense transcript. TMEM5/RXYLT1 is involved in glycosylation and diseases such as congenital muscular dystrophy, but is distinct from ENSG00000249753[1][5][7].\n\nIf you need structured information for TMEM5/RXYLT1 as a drug target, specify accordingly; this lncRNA entry is not therapeutically actionable.

Other names

Antisense to TMEM5ENSG00000249753