ANXA2R overlapping transcript 1 (ANXA2R-OT1)

ANXA2R overlapping transcript 1 (ANXA2R-OT1) is a human long non-coding RNA (lncRNA) gene, defined as a genomic transcript that overlaps the protein-coding region of the ANXA2R gene on the same strand[2][3]. According to the HUGO Gene Nomenclature Committee, overlapping transcripts in this context are specifically lncRNAs, which do not encode proteins and whose molecular and biological roles are often poorly characterized[2]. The ANXA2R-OT1 gene is affiliated with the lncRNA class and has been associated in the literature or by database annotation with descending colon cancer[3]. However, no data currently support any receptor, enzyme, or transporter activity, and there is no evidence it is a direct therapeutic target or interacts with drugs. Furthermore, it is important to distinguish this lncRNA from the nearby protein-coding gene ANXA2R or ANXA2 for which functional receptor or protein data may be available[4][6].

Other names

CTD-2201E18.3FLJ32255ANXA2R-OT1