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Apolipoprotein L6 (APOL6)

Target: APOL6
Molecular classification: Other (Apolipoprotein family)

Overview

Apolipoprotein L6 is a member of the apolipoprotein L gene family and is a cytoplasmic protein that may affect the movement of lipids within the cytoplasm or facilitate the binding of lipids to cellular organelles. It has proapoptotic properties and can induce mitochondria-mediated apoptosis, particularly in cancer cells, and has been associated with tumor aggressiveness and interactions with genes involved in the STAT signaling pathway and immune defense responses[1][2][3][4][5].

Other names: APOL6APOL-VIAPOLVIapolipoprotein L6apolipoprotein L, 6apolipoprotein L-VIApoL-VIApolipoprotein L-VIUNQ3095/PRO21341

Biological functions

Lipid transport and bindingRegulation of apoptosis (proapoptotic activity)

Disease associations

Cancer (notably tumor aggressiveness and apoptosis in cancer cells)Other (possible roles in inflammation and defense response)

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