Apolipoprotein O pseudogene 5 (APOOP5)

Apolipoprotein O pseudogene 5 (APOOP5) is a processed, transcriptionally active pseudogene derived from apolipoprotein O (APOO). Although pseudogenes have traditionally been considered non-functional, some—including APOOP5—may have regulatory activity at the RNA level, influencing the expression and function of their parent genes. Recent research indicates that a variant in APOOP5 is associated with increased LDL cholesterol in certain populations, possibly via interaction and regulatory influence upon APOO. However, unlike APOO, APOOP5 does not produce a functional protein and therefore is not considered a classical therapeutic target[5][3]. If you are seeking structured data or druggability, focus on the parent gene/protein, Apolipoprotein O (APOO), as APOOP5 itself is primarily relevant for genetics and regulatory studies rather than direct molecular targeting[5][3][1].

Other names

Apolipoprotein O pseudogene 5