Apoptosis-inducing factor, mitochondria-associated 1 pseudogene 1 (AIFM1P1)

AIFM1P1 is a pseudogene related to the protein-coding gene Apoptosis-inducing factor, mitochondria-associated 1 (AIFM1). Pseudogenes such as AIFM1P1 are DNA sequences similar to known genes but are non-functional, do not code for active proteins, and are not considered valid therapeutic targets. While a pseudogene related to AIFM1 has been identified on chromosome 10[1][2][3][5], it does not have a demonstrated biological function, is not druggable, and is not involved in disease or cellular pathways. All known biological and disease associations refer to the protein-coding gene AIFM1, not to the pseudogene AIFM1P1. Key clarification: There is likely an error if AIFM1P1 is proposed as a therapeutic target, as it is a non-coding pseudogene rather than a protein-coding gene or functional receptor/enzyme. Information on function, interacting drugs, disease association, or mechanism of action only exists for AIFM1, not for AIFM1P1[1][2][3][5].

Other names

AIFM1 pseudogene 1apoptosis inducing factor, mitochondria associated 1 pseudogene 1apoptosis-inducing factor, mitochondrion-associated, 1 pseudogene 1AIFM1P1