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Aquaporin 7 pseudogene 5 (AQP7P5) is classified as a pseudogene in humans, meaning it is a DNA sequence resembling the aquaporin 7 (AQP7) gene but does not produce an active protein[10]. Unlike functional aquaporins (such as AQP7), which facilitate the selective transport of water, glycerol, and urea across membranes and are involved in metabolic regulation, pseudogenes like AQP7P5 generally lack confirmed transcription or biological activity. Multiple pseudogenes related to aquaporin 7 exist adjacent to the active gene, but they are not considered molecular therapeutic targets, do not encode functional channels, and are typically ignored in drug discovery, biological function annotation, or disease association studies[10][4]. If your interest is in aquaporin-7 as a therapeutic target, refer directly to "Aquaporin 7" (AQP7), which is a functional water/glycerol/urea channel and clinically relevant protein[4][2][5].
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