ARB2 family member B, pseudogene (ARB2BP)

ARB2 family member B, pseudogene (ARB2BP) is classified as a pseudogene based on current annotation[3]. While there is prediction of involvement in siRNA binding and regulatory ncRNA-mediated heterochromatin formation, there is no evidence that this locus encodes a functional protein or participates directly in therapeutic or disease processes. Its aliases reflect historical and alternate annotations, but no validated function, protein product, or disease association is described in major gene databases or scientific literature[3]. Thus, ARB2BP is not considered a therapeutic target, and its molecular classification is limited to "pseudogene." ARB2BP is often listed with "protein" or "isoform" synonyms, but there is no evidence for a protein-coding function; current authoritative sources consistently label it a pseudogene[3]. It should not be considered a receptor, enzyme, transporter, or classical drug target. If use as a target is proposed, this would be incorrect based on present gene annotation and lack of functional protein product. For structured annotation or target catalogue integration, ARB2BP should be classified as a non-target pseudogene and excluded from lists of therapeutic drug targets.

Other names

FAM172BFAM172BPLOC131909FLJ45679Protein FAM172BPsimilar to CG10038-PB isoform B