Archaelysin family metallopeptidase 2 pseudogene (AMZ2 pseudogene)

The archaelysin family metallopeptidase 2 pseudogene (ENSG00000204399) is a segment of human DNA that closely resembles the sequence of archaelysin family metallopeptidase 2 (AMZ2) but has lost the ability to produce a functional protein due to mutations or truncations. Pseudogenes such as this typically arise by gene duplication or retrotransposition and eventually accumulate mutations that render them nonfunctional[3][4]. These genetic elements do not encode active proteins nor serve as direct drug targets, but may contribute to genomic evolution or, in rare cases, regulatory functions. For archaelysin family metallopeptidase 2 pseudogene, there is no evidence of biological, therapeutic, or diagnostic significance.

Other names

AMZ2PArchaelysin family metallopeptidase 2 (AMZ2) pseudogeneLOC100288192