ARF GTPase 1 pseudogene 1 (ARF1P1)

ARF GTPase 1 pseudogene 1 (ARF1P1) is a non-functional genomic sequence in humans that is similar in sequence to the functional ADP-ribosylation factor 1 (ARF1) gene. ARF1 itself encodes a small GTP-binding protein from the RAS superfamily, which plays critical roles in vesicular trafficking, membrane transport, and regulation of cellular processes. In contrast, ARF1P1 is classified as a pseudogene, meaning it does not produce a functional protein and has no active biological or therapeutic relevance. Pseudogenes are not considered therapeutic, functional, or pharmacologically tractable targets. They do not encode active proteins, do not participate directly in biological processes, and are rarely associated with disease mechanisms, except in very rare cases involving gene regulation (not described for ARF1P1). There is no evidence in the literature that ARF1P1 acts as a drug target, biomarker, or functional protein. The functional gene ARF1 (not ARF1P1) is involved in vesicular trafficking and signal transduction. As such, any structured dataset or knowledge graph focused on drug targets, mechanisms of action, or biomarkers should omit ARF1P1 as a target. In summary, ARF GTPase 1 pseudogene 1 (ARF1P1) is a non-functional DNA sequence derived from the functional ARF1 gene. It does not encode a protein and is not considered a therapeutic or biological target. The entry is incorrect for target work, as it does not represent a true target, receptor, enzyme, or transporter.

Other names

ADP-ribosylation factor 1 pseudogene 1ARF1P1