ARF GTPase 1 pseudogene 3 (ARF1P3)

ARF GTPase 1 pseudogene 3 (ARF1P3) is a pseudogene, meaning it is a genomic DNA sequence similar to that of a functional gene but typically regarded as non-functional and does not encode a functional protein[4]. ARF1P3 shares sequence similarity with the protein-coding ARF1 gene, which encodes ADP-ribosylation factor 1—a member of the Ras superfamily of small GTPases involved in membrane trafficking and Golgi apparatus function[3]. However, as a pseudogene, ARF1P3 itself does not produce a functional GTPase and has no documented biological activity, disease association, or role as a drug target[4]. ARF1P3 is not considered a therapeutic target such as a receptor, enzyme, transporter, or transcription factor[4]. There is nothing to indicate it acts as a biomarker or intermediary in cell signaling or pathology. Additionally, no drugs are known to interact with ARF1P3, nor are there mechanisms of action established for such molecules. Its relevance is mainly as a genomic element, not a protein or molecular target in drug discovery or clinical research. Because ARF1P3 is a pseudogene and not a functional molecule, listing it as a therapeutic target is incorrect, and it should not be selected as such for indexing or structure-activity studies for drug discovery or pharmacological profiling[4]. No canonical aliases or alternative names beyond ARF1P3 exist; classification is as a pseudogene, placing it in the "Other" category for molecular family. It is not part of recognized protein categories such as G protein-coupled receptors, ion channels, transporters, enzymes, or transcription factors.

Other names

ARF1P3