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ARL6IP1P3 (ARF like GTPase 6 interacting protein 1 pseudogene 3) is a non-protein-coding pseudogene, meaning it is a genomic DNA sequence similar to a known gene but is non-functional due to mutations or lack of regulatory sequences necessary for gene expression. It does not encode a functional protein and is not implicated as a therapeutic target, nor does it have described biological or disease roles[5]. ARL6IP1P3 should not be confused with the functional ARL6IP1 gene, which encodes a membrane-associated protein involved in glutamate transport, apoptosis regulation, and is linked to hereditary spastic paraplegia. The pseudogene ARL6IP1P3 is a separate, non-coding remnant, with no evidence supporting its role as a clinically actionable target[1][5].
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