Target intelligence / Profile preview

ARF like GTPase 6 interacting protein 6 (ARL6IP6)

Target
ARL6IP6
Molecular classification
Other (ARF family-interacting protein; not a classic receptor, enzyme, transporter, or transcription factor)[5][7]
01

Overview

ARF like GTPase 6 interacting protein 6 (ARL6IP6) is a human gene encoding a protein predicted to interact with ADP-ribosylation factor-like GTPase 6 (ARL6), a member of the ARF family of GTP-binding proteins involved in membrane trafficking. ARL6IP6 itself is predicted to be located at the nuclear inner membrane, but its precise biological functions remain poorly characterized in the literature. While associations with rare diseases such as cutis marmorata telangiectatica congenita and autism spectrum disorder are noted, there is currently no evidence supporting its role as a drug target, and no known drugs, clinical biomarkers, or specific safety concerns are described[5][7][9].

Other names
ADP ribosylation factor like GTPase 6 interacting protein 6ADP-ribosylation factor-like 6 interacting protein 6ADP-ribosylation factor-like protein 6-interacting protein 6ARL-6-interacting protein 6Phosphonoformate immuno-associated protein 1MGC33864[5][7][9]
02

Biological functions

Predicted involvement in membrane-associated trafficking (based on family association; not experimentally detailed)[7]
03

Disease associations

Cutis marmorata telangiectatica congenitaAutism spectrum disorder[7]

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