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Target intelligence / Profile preview
Arginine (Arg)
- Target
- Arg
- Molecular classification
- Amino acid, Building block of proteins, Precursor molecule
01
Overview
Arginine is a semi-essential amino acid that plays critical roles in several metabolic pathways. It is a key building block of proteins and a precursor for nitric oxide, which regulates vasodilation and blood pressure. Arginine is involved in cell division, wound healing, immune function, hormone release, and removal of ammonia via the urea cycle.
- Other names
- L-arginineL(+)-arginineL-Argenin(e)HARGOH
02
Mechanism of action
As a precursor for nitric oxide, arginine promotes vasodilation by increasing nitric oxide production. Involved in protein synthesis and urea cycle.
03
Biological functions
Nitric oxide synthesisUrea cycleProtein synthesisImmune functionHormone releaseWound healingCell divisionPrecursor for creatinePrecursor for polyaminesPrecursor for prolinePrecursor for glutamatePrecursor for agmatinePrecursor for ornithinePrecursor for urea
04
Disease associations
Cardiovascular diseaseErectile dysfunctionHypertensionPreeclampsiaWound healingImmune deficiencyAsthmaHerpes virus infections
05
Safety considerations
Gastrointestinal discomfortMay worsen asthma symptomsMay trigger herpes outbreaksPossible increased mortality risk after recent heart attackInteractions with antihypertensive drugs
06
Interacting drugs
Antihypertensive drugs
2 more in the full profile.
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