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The **arginine-glutamic acid dipeptide repeats pseudogene** (ENSG00000258732) is a non-functional genomic locus with sequence similarity to the protein-coding gene RERE. According to current nomenclature guidelines and gene annotation sources, this pseudogene is not expected to produce a functional protein, nor is it recognized as having a role in human disease or as a therapeutic target. Pseudogenes may occasionally serve as sources of regulatory non-coding RNAs, but no such function has been described for this specific sequence. For biomedical and drug discovery purposes, ENSG00000258732 is not considered a pharmacologically relevant target[1][3][7]. **Critical points and conventions:** - Pseudogenes, by definition, are not therapeutic targets and should not be confused with active genes, receptors, or proteins[1]. - The canonical receptor/protein is **RERE** (arginine-glutamic acid dipeptide repeats), which is distinct from this pseudogene[2][6][8].
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