Argininosuccinate synthetase 1 pseudogene 10 (ASS1P10)

Argininosuccinate synthetase 1 pseudogene 10 (ASS1P10) is a non-coding copy (pseudogene) of the functional ASS1 gene, which encodes the enzyme argininosuccinate synthetase 1 important in the urea cycle. ASS1P10 itself does not encode a functional protein and has no reported biological function, disease association, or direct therapeutic relevance[4]. Pseudogenes like ASS1P10 are DNA sequences similar to functional genes but typically lack coding potential due to disabling mutations, deletions, or lack of regulatory elements, so they do not contribute to enzyme activity, cellular signaling, or pathology in a manner similar to true targets[4]. The functional gene (ASS1) and its protein product are relevant in urea cycle metabolism and associated diseases, but this does not apply to ASS1P10[1][2][6]. Database entries for ASS1P10 confirm its status as a pseudogene and do not list any therapeutic, diagnostic, or biological functions or uses[4]. ASS1P10 should not be used as a molecular target in any biomedical context. If a function or disease role is needed, consider *argininosuccinate synthetase 1 (ASS1)*, not its pseudogenes.

Other names

ASSP10argininosuccinate synthetase pseudogene 10ASS1P10[4]