Argininosuccinate synthetase 1 pseudogene 2 (ASS1P2)

Argininosuccinate synthetase 1 pseudogene 2 (ASS1P2) is classified as a pseudogene, meaning it is a DNA sequence similar to a known gene (argininosuccinate synthetase 1, or ASS1) but is not believed to encode a functional protein[5]. Pseudogenes arise through duplication or retrotransposition events, and typically do not produce active products due to mutations or lack of regulatory elements. Human genome annotations report multiple ASS1-related pseudogenes scattered throughout, with only the chromosome 9 copy (ASS1) encoding a functional enzyme; ASS1P2 is not among these functional genes[2][5]. Therefore, ASS1P2 is not considered a therapeutic target and does not play a known biological or disease role. If you intended to inquire about the functional enzyme argininosuccinate synthetase 1 (ASS1), that is a separate, well-studied gene involved in the urea cycle and disease (such as citrullinemia), in contrast to ASS1P2[1][2][3][4][6][7].

Other names

ASSP2argininosuccinate synthetase pseudogene 2ASS1P2