Argininosuccinate synthetase 1 pseudogene 9 (ASS1P9)

Argininosuccinate synthetase 1 pseudogene 9 (ASS1P9) is one of several pseudogenes related to the argininosuccinate synthase 1 gene (ASS1), which is an important enzyme in the urea cycle and arginine biosynthesis. Pseudogenes like ASS1P9 resemble the functional gene in sequence but typically do not produce an active protein and are not known to have physiological or pathological functions. Among the multiple ASS1-related sequences in the human genome, only the gene located on chromosome 9 encodes a functional enzyme; the remaining copies, including ASS1P9, are considered non-functional pseudogenes[1][2][3][6]. Pseudogenes (like ASS1P9) are generally not considered therapeutic targets, as they typically do not encode functional proteins or participate in relevant molecular pathways. The functional protein (argininosuccinate synthase 1, ASS1) is encoded by a different, active locus on chromosome 9[1][3][6]. Therapeutic strategies and drug research are directed toward the functional enzyme ASS1, not its pseudogenes. No known drugs or disease associations, biomarkers, or safety concerns are reported for pseudogene 9. If you are seeking information about the functional enzyme (argininosuccinate synthase 1, ASS1), it is a distinct molecular entity, whereas ASS1P9 specifically refers to a non-functional pseudogene[1][3][6].

Other names

ASSP9argininosuccinate synthetase pseudogene 9ASS1P9