ARHGAP26 intronic transcript 1 (ARHGAP26-IT1)

ARHGAP26 intronic transcript 1 (ARHGAP26-IT1) is a long non-coding RNA (lncRNA) transcript located within the ARHGAP26 gene locus. It does not code for a protein, and there is currently no experimental or clinical evidence connecting it to specific molecular functions, signaling pathways, or disease processes. It is annotated in major gene nomenclature and cataloging resources as a non-coding RNA, and is not considered a classical drug target such as a receptor, enzyme, or transporter[3][5][6]. ARHGAP26-IT1 is distinct from ARHGAP26, which encodes a protein (Rho GTPase activating protein 26 or GRAF1)[1][2]; ARHGAP26 is a bona fide regulator of cytoskeletal processes and has disease relevance, but ARHGAP26-IT1 is solely an lncRNA[3][6]. No current literature or major database links ARHGAP26-IT1 to known biological functions, diseases, drugs, or therapeutic mechanisms on par with traditional molecular targets (e.g., GPCRs, kinases, etc.)[3][5][6]. No evidence of misannotation or gene confusion for the ARHGAP26-IT1 transcript was found in authoritative databases or NCBI gene reports. If you intended to query the protein-coding gene ARHGAP26 (GRAF1) instead of the lncRNA ARHGAP26-IT1, clarification is suggested as these are distinct entities[1][2][3].

Other names

ARHGAP26-IT1ARHGAP26 intronic transcript 1