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ARHGAP28 antisense RNA 1 (ARHGAP28-AS1)

Target: ARHGAP28-AS1
Molecular classification: Long non-coding RNA (lncRNA)

Overview

ARHGAP28 antisense RNA 1 (ARHGAP28-AS1) is a long non-coding RNA (lncRNA) gene located in the human genome. Antisense RNAs such as ARHGAP28-AS1 typically regulate the expression of nearby protein-coding genes, often through mechanisms including RNA-RNA interactions or chromatin modification, but specific functions or disease associations for this RNA remain uncharacterized in the present literature. It should not be confused with the protein-coding ARHGAP28 gene, which encodes a Rho GTPase-activating protein involved in regulation of actin cytoskeleton, cell migration, and potentially in tumor suppression. No clinical drugs, biomarker roles, or established therapeutic mechanisms are documented for ARHGAP28-AS1.\n\nIf you are seeking information on the protein-coding ARHGAP28 (Rho GTPase activating protein 28), please clarify, as that molecule is better characterized in cell biology and disease contexts.

Other names: ARHGAP28-AS1

Mechanism of action

Not applicable (no drugs known to target ARHGAP28-AS1)

Biological functions

Currently, specific biological functions of ARHGAP28-AS1 as an antisense RNA are not well characterized in the literature. By general classification, antisense RNAs often play roles in regulating expression of their sense gene (in this case, ARHGAP28).

Disease associations

No direct disease roles are currently established for ARHGAP28-AS1 as a non-coding RNA.

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