Ariadne RBR E3 ubiquitin protein ligase 2 pseudogene 1 (ARIH2P1)

Ariadne RBR E3 ubiquitin protein ligase 2 pseudogene 1 (ARIH2P1) is classified as a pseudogene, meaning it is a nonfunctional segment of DNA that resembles its parent gene (ARIH2, which encodes a ubiquitin ligase protein), but ARIH2P1 itself does not encode a functional protein due to disabling mutations[1][3][5]. Pseudogenes like ARIH2P1 may be transcribed into non-coding RNAs and, in rare cases, participate in gene regulation (such as acting as microRNA decoys or generating regulatory RNAs), but no evidence is available that ARIH2P1 itself has such functions[2][5]. It is not considered a therapeutic target, does not interact with drugs, and has no known relevance as a disease biomarker or safety concern. Pseudogenes can occasionally complicate genetic studies due to sequence similarity with their functional counterparts[5].

Other names

ARIH2P

None known (Not a druggable protein, not targeted by small molecules or biologics)