Target intelligence / Profile preview

ARL14EP divergent transcript (ARL14EP-DT)

Target
ARL14EP-DT
Molecular classification
Other (noncoding RNA, transcriptome annotation)
01

Overview

ARL14EP divergent transcript (ARL14EP-DT) is a genomically annotated noncoding RNA transcript arising from bidirectional (divergent) transcription at the ARL14EP locus. Divergent transcripts are typically unstable, carry no coding information, and are not functionally characterized. There is no evidence for ARL14EP-DT as a pharmacological, clinical, or experimental target. The bona fide gene product, ARF Like GTPase 14 Effector Protein (ARL14EP), interacts with ARL14 and MYO1E to regulate major histocompatibility class II vesicle trafficking in dendritic cells, but ARL14EP-DT itself lacks confirmed function or disease association[1][2][3][4].

Other names
ARL14EP-DTARL14EP divergent transcript
02

Mechanism of action

None

03

Biological functions

Other (divergent transcription may play a role in genome evolution and regulation, but specific functions of ARL14EP-DT are unknown)
04

Disease associations

Other (no direct evidence of disease association for ARL14EP-DT; diseases linked to ARL14EP include Seckel Syndrome and Autism Spectrum Disorder, but these refer to the coding gene)

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