ArsA arsenite transporter, ATP-binding, homolog 1, pseudogene (ArsA (pseudogene))

ENSG00000271350 corresponds to a **pseudogene** of the ArsA arsenite transporter, ATP-binding, homolog 1, known as an inactive genomic sequence derived from the bacterial ArsA ATPase. While functional **ArsA** (in prokaryotes and a few eukaryotes) forms part of a transporter complex (ArsAB) that catalyzes the ATP-dependent efflux of arsenite and antimonite to confer arsenic resistance[5][4], in humans **ENSG00000271350 is a a pseudogene and does not encode a functional protein**[2]. There is no evidence that this pseudogene produces a transporter, has physiological function, or represents a therapeutic target. Key details: - **Pseudogene:** It is explicitly listed as a pseudogene in current genomic databases[2][1]. - **Not a therapeutic target:** No known transporter, enzyme, or receptor is produced by this locus in humans. There is no evidence of involvement in disease, drug interaction, or biological function[2][1]. - **No biological or disease roles:** Its bacterial homologue is important in arsenic resistance, but the human pseudogene is nonfunctional and has no physiological or pathological role[5][4]. - **Aliases:** Alternate identifiers and previous gene cards records exist, but all refer to inactive or uncharacterized sequences[2]. - **No molecular family:** As a pseudogene, it does not belong to transporter, enzyme, receptor, or other protein families. Summary assessment: - This gene is **not a functional target**, has **no biological or therapeutic relevance**, and is **considered a pseudogene with no product** in humans[2]. - The bacterial ArsA ATPase does have mechanistic and structural characterization as part of ATP-driven arsenite/antimonite efflux in prokaryotes, but no such transporter exists for this locus in humans[5][4].

Other names

ArsA ATPase pseudogeneArsA arsenite transporter pseudogeneATP-binding arsenite transporter pseudogene