Arylacetamide deacetylase-like 4 (AADACL4)

Arylacetamide deacetylase-like 4 is a protein encoded by the *AADACL4* gene in humans. It belongs to the GDXG lipolytic enzyme family and functions as a hydrolase, hydrolyzing esters and amides. Structurally, AADACL4 is a single-pass type II membrane protein with domains including a signal-anchor and transmembrane helix, associated typically with membrane localization[1]. As with other members of the arylacetamide deacetylase family, the enzyme is predicted to participate in the metabolism of endogenous and xenobiotic lipid substrates, indicated by its homology. However, its specific substrates, physiological roles, or disease associations remain largely unstudied. No documented drug interactions nor validated biomarker roles have been described for this molecule, and it is not recognized as a therapeutic target in current literature[1][2].

Other names

AADACL4OTTHUMG00000001889arylacetamide deacetylase-like 4OTTMUSG00000010747RGD1565761