Ascorbyl glucoside

Ascorbyl glucoside is a water-soluble, stabilized derivative of vitamin C formed by bonding ascorbic acid with glucose. It is chemically synthesized using a biocatalytic transglucosylation, resulting in enhanced stability over traditional ascorbic acid[1][2][4][5]. Used widely in cosmetic products, it demonstrates potent antioxidant properties, inhibits melanin production, brightens skin tone, and promotes collagen synthesis. Its stability against heat, pH, and metal ions makes it desirable for skincare formulations. Upon topical application, ascorbyl glucoside is enzymatically hydrolyzed in skin cells, slowly releasing active vitamin C, which provides long-lasting antioxidant and anti-aging benefits[5].

Other names

Ascorbic acid 2-glucosideAA-2GVitamin C glucosideAscorbate glucoside2-O-α-D-Glucopyranosyl-L-ascorbic acidVCGLGB-AA2GAscofresh

Enzymatic hydrolysis by α-glucosidase in the skin releases active vitamin C (ascorbic acid), providing antioxidant activity, stimulating collagen synthesis, and inhibiting melanin production[5].