ASH1L intronic transcript 1 (ASH1L-IT1)

ASH1L intronic transcript 1 (ASH1L-IT1) is a long non-coding RNA arising from an intronic region of the *ASH1L* gene. Unlike the canonical protein-coding ASH1L, which encodes a histone methyltransferase involved in chromatin modification, development, and diverse human diseases, little is concretely established regarding the biological function, disease associations, or therapeutic targetability of ASH1L-IT1. The term is often confused with the protein-coding ASH1L, which is itself a validated drug discovery and disease biomarker target due to its enzymatic function in chromatin biology and cancer[2][1][4]. ASH1L-IT1 is not considered a standard therapeutic target or part of any known drug-interaction pathways, and information is notably sparse and ambiguous in both the literature and databases. If you instead meant the canonical protein-coding ASH1L, clarify, as this is a well-characterized histone methyltransferase implicated in cancer, neurodevelopmental disorders, and other major roles[2][1][4][5][6][7].

Other names

lncRNA ASH1L-IT1ASH1L intronic transcript 1