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ASTN2 antisense RNA 1 (ASTN2-AS1)

Target
ASTN2-AS1
Molecular classification
Other (long non-coding RNA; antisense RNA)
01

Overview

ASTN2 antisense RNA 1 (ASTN2-AS1) is a long non-coding antisense RNA gene that is transcribed on the opposite strand of the protein-coding gene ASTN2. Its main postulated function is the regulation of the expression of ASTN2, likely through modulation of its mRNA stability, processing, or translation. Like other antisense RNAs, ASTN2-AS1 may play a role in fine-tuning gene expression but does not encode a protein or function as a classical drug target such as a receptor or enzyme. There is minimal direct experimental data characterizing its biological or disease impact as of now[3][6].

Other names
ASTN2-AS1
02

Mechanism of action

None established for drugs; possible gene regulation via antisense transcript effects

03

Biological functions

Putative regulation of the sense-strand gene ASTN2 (Astrotactin 2)Modulation of gene expression via antisense interaction
04

Disease associations

Potential involvement in neurological development (inferred from the function of ASTN2, but not directly demonstrated for ASTN2-AS1)

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