ATP binding cassette subfamily C member 6 pseudogene 1 (ABCC6P1)

ATP binding cassette subfamily C member 6 pseudogene 1 (ABCC6P1) is a **transcriptionally active pseudogene** related to the ABCC6 gene, which encodes an ATP-dependent transporter implicated in molecular export and human disease, notably pseudoxanthoma elasticum[1][3]. Unlike ABCC6, ABCC6P1 does **not encode a functional protein** but it is co-expressed with ABCC6 in several tissues—particularly liver and kidney—and can influence the mRNA levels of the parental ABCC6 gene, as demonstrated by siRNA knockdown studies indicating regulatory interdependence[1]. ABCC6P1 is not a therapeutic target (such as a receptor, enzyme, or transporter) and is best considered a *regulatory non-coding RNA* rather than a classic protein-coding drug target[1][3]. No drugs or direct biomarker roles are documented for ABCC6P1; its main biological significance lies in modulating the expression of the adjacent ABCC6 gene via its transcript.

Other names

ABCC6 pseudogene 1pseudoxanthoma elasticum pseudogene ABCC6P1