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Cellular ATP-dependent enzymes are proteins that utilize the energy derived from ATP hydrolysis to perform essential cellular functions. The group includes molecular motors and remodelers (such as chromatin-remodeling complexes like SWI/SNF, ISWI, CHD, and INO80), transporters (like the ATP-binding cassette, or ABC transporter family), ATP-dependent proteases, and other molecular machines involved in nucleic acid metabolism, DNA repair, and protein homeostasis[2][3][4][5][7]. These enzymes are highly conserved across species and are critical to processes such as gene regulation, protein degradation, and transport of molecules across membranes. Due to their broad and essential roles in cell biology, the term lacks specificity and should be replaced by a precise enzyme name for structured annotation or therapeutic targeting.
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