ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 pseudogene

This locus (ENSG00000213556, also known as LOC100288416 or ATP synthase F chain pseudogene) is a human pseudogene closely related to the protein-coding gene for ATP synthase membrane subunit F (ATP5MF). ATP synthase is a large mitochondrial enzyme complex responsible for ATP production through oxidative phosphorylation, comprising multiple subunits grouped into the F1 (catalytic) and Fo (membrane proton channel) domains. However, the pseudogene version does not encode a functional protein, having accumulated disabling mutations or resulting from genomic duplication or retrotransposition. Pseudogenes like this may be transcribed in some contexts, but they do not produce a protein product and are not pursued as drug targets. No evidence currently supports a role for this pseudogene in disease or as a biomarker. If you are seeking information relevant to therapeutic targets, you should instead consult the protein-coding ATP5MF gene ("ATP synthase membrane subunit F") and not this pseudogene.

Other names

ATP synthase F chain pseudogeneLOC100288416ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 pseudogene