ATP6V0E2 antisense RNA 1 (ATP6V0E2-AS1)

ATP6V0E2 antisense RNA 1 (ATP6V0E2-AS1) is a long non-coding RNA (lncRNA) gene transcribed from the antisense strand of the ATP6V0E2 locus. This RNA belongs to the lncRNA and natural antisense transcript molecular classes, meaning it does not code for a protein but may regulate expression of its sense counterpart gene (ATP6V0E2) or other local/regional genes. General roles for antisense RNAs include modulation of splicing, transcription, RNA stability, and translation, often in cis, but the specific molecular and biological function of ATP6V0E2-AS1 remains incompletely characterized. According to public gene databases, variants or altered expression of ATP6V0E2-AS1 may be associated with rare metabolic diseases, such as infantile hypophosphatasia. However, there is no direct evidence that ATP6V0E2-AS1 is a therapeutic target, nor are there any known drugs, clinical biomarkers, or notable safety concerns currently linked to this RNA[7][2][8].

Other names

ATP6V0E2-AS1ATP6V0E2 antisense RNA 1 (non-protein coding)