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ATPase, aminophospholipid transporter, class I, type 8A, member 2 pseudogene 3 (ATP8A2P3)

Target
ATP8A2P3
Molecular classification
Other (Pseudogene)
01

Overview

ATPase, aminophospholipid transporter, class I, type 8A, member 2 pseudogene 3 (ATP8A2P3) is annotated as a human pseudogene, meaning it is a non-functional copy of a protein-coding gene, in this case related to ATP8A2, which encodes an aminophospholipid translocase involved in membrane phospholipid transport[1][2][5]. Pseudogenes do not encode functional proteins but may exert regulatory effects on gene expression through non-coding RNA functions, such as acting as competitive endogenous RNA (ceRNA) or microRNA decoys, though this has not specifically been shown for ATP8A2P3[4]. There is no evidence this pseudogene encodes an active transporter or serves as a drug target, and it is not associated directly with any human disease or clinically relevant function. In summary, ATP8A2P3 is a noncoding pseudogene, not a therapeutic target, and does not possess biological or pharmacological functions attributed to protein-coding members of the ATPase family. There are no known drugs, biomarkers, or safety concerns associated with this pseudogene.

Other names
ATP8A2P3ATPase, aminophospholipid transporter, class I, type 8A, member 2 pseudogene 3
02

Biological functions

Regulation of gene expression through non-coding RNA mechanisms, such as microRNA decoy activity or generation of regulatory RNAs (possible, but not established for this specific pseudogene)
03

Disease associations

Other (dysregulation of pseudogenes in general can be linked to cancer and various disease states, but no direct evidence for ATP8A2P3 specifically)

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