ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 pseudogene

ENSG00000255454 encodes a non-functional **pseudogene** (LOC107984367), related by sequence homology to **ATP6V1G1**, which encodes the V1 subunit G1 of the vacuolar H⁺-transporting ATPase (V-ATPase) complex. Pseudogenes like this are DNA segments similar to functional genes but lack protein-coding potential due to mutations or truncations. Therefore, this 'target' is not suitable for therapeutic targeting or biomarker usage. If functional, its gene family (V-ATPase G1 subunit) facilitates organelle acidification critical for protein sorting, autophagy, and synaptic vesicle proton gradient generation. However, the pseudogene form does not contribute to these biological activities or disease processes and has no direct clinical significance. Overall, this entity is a non-coding pseudogene and not a valid therapeutic or biomarker target.

Other names

LOC107984367ATP6V1G1 pseudogeneATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 pseudogeneATP6V1G1P