ATPase copper transporting beta pseudogene 1 (ATP7BP1)

ATPase copper transporting beta pseudogene 1 (ATP7BP1) is a non-protein-coding locus classified as a pseudogene, which means it shares sequence similarity with functional copper-transporting ATPase genes but has lost the ability to encode a functional protein due to disabling mutations[1][5]. Unlike its protein-coding relatives, such as ATP7B or ATP7A, ATP7BP1 does not carry out copper ion transport[1][5]. Pseudogenes are typically considered non-functional remnants, though emerging evidence in the pseudogene field suggests some pseudogenes may play non-coding regulatory roles, mainly through RNA-mediated mechanisms impacting expression of related genes in select cases[2][3][4]. No such function or disease association has been described for ATP7BP1. It is located on chromosome 18q11.2[5]. If you need structured database fields, this information allows accurate mapping to canonical form while flagging that this entry is a non-functional pseudogene, not a molecular therapeutic target, and contains no actionable drug or biomarker information.

Other names

ATPase, Cu++ transporting, beta polypeptide pseudogene 1ATP7BP1