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ATPase H+ transporting V1 subunit E1 pseudogene 3 (ATP6V1E1P3)

Target: ATP6V1E1P3
Molecular classification: Pseudogene

Overview

ATPase H+ transporting V1 subunit E1 pseudogene 3 (ATP6V1E1P3) is a processed pseudogene related to the functional gene encoding a subunit of the vacuolar-type H+-ATPase (V-ATPase) complex[1][3][5]. Unlike its protein-coding parental gene, ATP6V1E1P3 has sequence changes that prevent translation into a functional protein and is considered non-coding[1][5]. While some pseudogenes are known to be transcribed and may influence the expression of their parent genes or other regulatory pathways, there is currently no evidence that ATP6V1E1P3 produces a functional RNA or protein product, or that it serves as a therapeutic or diagnostic target in human disease[2][4].

Other names: ATP6EL1ATP6V1EL1

Mechanism of action

Not applicable

Biological functions

Although most pseudogenes are non-functional, some may regulate gene expression through RNA-mediated mechanisms such as microRNA decoy roles or competing endogenous RNA effects. No direct evidence exists for functional roles of ATP6V1E1P3 specifically.

Disease associations

Indirectly, pseudogenes have been implicated in cancer and disease by regulating parental gene expression, but there is no evidence linking ATP6V1E1P3 to any disease phenotype.

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