ATPase PAAT (PAAT)

ATPase PAAT (commonly referred to as C10orf88 or protein associated with ABC transporters) is a mitochondrial ATPase that regulates the activity of mitochondrial ABC transporters such as ABCB7, ABCB8, and ABCB10[1][3][8][12]. By modulating these transporters, ATPase PAAT influences mitochondrial iron concentration, heme biosynthesis, and overall mitochondrial health, contributing to cellular survival and mitochondrial homeostasis[1][3][12]. While the gene is clearly annotated and has emerging links to various disease states, its precise therapeutic or diagnostic significance remains under study[3][10][12].

Other names

Chromosome 10 open reading frame 88C10orf88Protein associated with ABC transportersFLJ13490Em:AC073585.5Uncharacterized protein C10orf88