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ATXN7L3 antisense RNA 1 (ATXN7L3-AS1)
- Target
- ATXN7L3-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA
01
Overview
ATXN7L3 antisense RNA 1 (ATXN7L3-AS1) is a long non-coding antisense RNA gene transcribed from the ATXN7L3 locus[7]. Like other antisense RNAs, it potentially regulates gene expression of its sense counterpart, ATXN7L3, through mechanisms such as affecting transcription, mRNA stability, and translation[3][6]. Broadly, antisense long non-coding RNAs can modulate molecular processes in cis or trans, impacting phenotype and potentially linking to disease pathways, although direct evidence for functional roles or disease associations of ATXN7L3-AS1 remains limited[3][6][7]. It is not considered a receptor, enzyme, transporter, or other typical therapeutic target, and there are no established drugs or biomarker associations for this gene[7].
- Other names
- ATXN7L3-AS1ATXN7L3 antisense RNA 1
02
Biological functions
Regulates gene expression (typically via antisense-based modulation of sense gene transcripts)May affect replication, transcription, or translation via RNA-RNA or RNA-chromatin interaction
03
Disease associations
Potential roles in cancer biology suggested in broader antisense RNA literatureSpecific disease roles for ATXN7L3-AS1 are not well established
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