Tumor antigen-presenting dendritic cell (autologous)

Tumor antigen-presenting dendritic cells (DCs), particularly when autologous, are a form of personalized immunotherapy in which a patient's own dendritic cells are harvested, loaded ex vivo with antigens derived from their own tumor, and then reintroduced to stimulate an anti-tumor immune response. These DCs act as professional antigen-presenting cells that process and present tumor-associated antigens to T-cells, thereby initiating and directing adaptive immune responses against cancer.

Other names

Autologous dendritic cell vaccinePersonalized dendritic cell immunotherapyTumor-loaded dendritic cells

Ex vivo loading of autologous dendritic cells with tumor antigens, followed by maturation and re-infusion to stimulate anti-tumor T-cell responses.