B Cell Activation Pathway (N/A)

The B cell activation pathway refers to the series of molecular and cellular events that occur when a B lymphocyte (B cell) encounters an antigen, leading to its activation, proliferation, and differentiation into antibody-secreting plasma cells or memory B cells. This process is central to the adaptive immune response. It involves the B cell receptor (BCR), co-receptors, and various signaling molecules like kinases (Lyn, Syk, Btk) and adaptor proteins (BLNK) to transduce signals upon antigen binding, leading to downstream effects like proliferation, class-switch recombination, somatic hypermutation, and differentiation into plasma or memory B cells.

Other names

B cell receptor signaling pathwayBCR signalingB lymphocyte activation pathway

N/A