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Target intelligence / Profile preview
Bacterial beta-lactamase (β-lactamase)
- Target
- β-lactamase
- Molecular classification
- Enzyme
01
Overview
Bacterial beta-lactamase is an enzyme produced by bacteria that confers resistance to beta-lactam antibiotics by hydrolyzing the beta-lactam ring, rendering these antibiotics ineffective. It is a significant therapeutic target in the fight against antibiotic resistance.
- Other names
- Beta-lactamaseβ-lactamase
02
Mechanism of action
Inhibition of beta-lactamase activity to restore effectiveness of beta-lactam antibiotics
03
Biological functions
Antibiotic resistancehydrolysis of beta-lactam antibiotics
04
Disease associations
Infectionantimicrobial resistance
05
Safety considerations
Spread of antibiotic resistancelimited effectiveness of certain antibiotics against beta-lactamase-producing bacteria
06
Interacting drugs
Penicillins
3 more in the full profile.
07
Biomarkers
Presence of beta-lactamase-producing bacteriaantibiotic resistance patterns
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