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Target intelligence / Profile preview
Bacterial DNA Replication Enzymes
- Molecular classification
- Enzyme
01
Overview
Bacterial DNA replication enzymes are a set of proteins crucial for duplicating the bacterial genome before cell division. Key enzymes include DNA helicase, topoisomerase II (DNA gyrase), RNA primase, DNA polymerase III, DNA polymerase I, and DNA ligase. These enzymes ensure high-fidelity duplication of bacterial genomes and are often targeted by antibiotics.
02
Mechanism of action
Inhibition of DNA gyrase/topoisomerases
03
Biological functions
DNA replicationGenome maintenanceCell division
04
Disease associations
Infection
05
Safety considerations
Antibiotic resistance
06
Interacting drugs
Quinolones
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