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Bacterial enzymes involved in essential cellular processes are a diverse group of proteins that catalyze biochemical reactions fundamental to the survival and proliferation of bacterial cells. These enzymes are encoded by essential genes—genes indispensable for cell viability—and play critical roles in metabolism, DNA replication, energy production, and other core cellular functions. Inhibiting these enzymes can halt bacterial growth or kill bacteria outright. These enzymes are attractive targets for antibiotic development.
Blocking active sites; Preventing substrate binding; Interference with cell wall biosynthesis, nucleic acid replication, or energy production.
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