Bacterial pathogen associated with diabetic foot ulcer

"Bacterial pathogens associated with diabetic foot ulcers" is a descriptive term for the wide range of bacterial species—often both Gram-positive (such as *Staphylococcus aureus*, including MRSA, and streptococci) and Gram-negative (such as *Pseudomonas aeruginosa*, *Escherichia coli*, *Klebsiella pneumoniae*, and *Proteus* spp.)—that are commonly isolated from infected diabetic foot ulcers. These infections are frequently polymicrobial (caused by multiple bacteria), sometimes include anaerobic bacteria and fungi, and are associated with increased risk of limb amputation and therapeutic challenges due to high rates of antibiotic resistance. These are not canonical molecular targets in the usual sense of drug discovery but are instead clinical microbiological entities that guide the selection of antimicrobial therapy.

Other names

Bacterial pathogens in diabetic foot ulcerDiabetic foot ulcer bacteriaDFU pathogensBacterial DFU pathogens

Inhibition of bacterial cell wall synthesis, Inhibition of protein synthesis, Inhibition of nucleic acid synthesis, Disruption of bacterial membranes, β-lactamase inhibition