Target intelligence / Profile preview

Bacterial Ribosome (16S rRNA of 30S Subunit) (16S rRNA)

Target
16S rRNA
Molecular classification
Ribonucleic acid, rRNA
01

Overview

The 16S ribosomal RNA (16S rRNA) is a fundamental component of the small (30S) subunit of prokaryotic ribosomes. It plays both structural and functional roles in protein synthesis, acting as a scaffold for ribosomal proteins and participating directly in the decoding process during translation. It is a target for several antibiotics.

Other names
16S ribosomal RNASmall subunit ribosomal RNA (bacteria)30S ribosomal subunit RNA
02

Mechanism of action

Inhibition of bacterial protein synthesis by interfering with decoding accuracy, translocation, or ribosome assembly.

03

Biological functions

Protein synthesisTranslation initiationmRNA decodingRibosome biogenesisSubunit association
04

Disease associations

Infection
05

Safety considerations

Antibiotic resistanceOff-target effects of antibiotics
06

Interacting drugs

Paromomycin

2 more in the full profile.

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