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Bacterial Ribosome 30S Subunit (30S)
- Target
- 30S
- Molecular classification
- Ribonucleoprotein, rRNA complex
01
Overview
The bacterial ribosome is a large ribonucleoprotein complex responsible for protein synthesis in prokaryotic cells. The 30S subunit plays a central role in decoding messenger RNA (mRNA) and ensuring accurate translation of genetic information into proteins. It is composed of one molecule of 16S ribosomal RNA (rRNA) and twenty-one ribosomal proteins (S1-S21). The 30S subunit is a major target for antibacterial drug development.
- Other names
- Small ribosomal subunit30S ribosomal subunit
02
Mechanism of action
Interference with decoding or translocation steps by binding specific sites on or near functional centers within the 30S ribosomal subunit, inhibiting bacterial protein synthesis.
03
Biological functions
Decoding mRNATranslation initiationTranslocation during protein synthesisProtein synthesis
04
Disease associations
Infection
05
Safety considerations
Antibiotic resistanceOff-target effects of antibiotics
06
Interacting drugs
Streptomycin
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