Basic transcription factor 3 pseudogene 11 (BTF3P11)

Basic transcription factor 3 pseudogene 11 (BTF3P11) is a processed pseudogene in the human genome, not known to produce a functional protein. Some of its aliases (OPG, OCIF, TNFRSF11B) actually refer to the functional protein osteoprotegerin, encoded by the TNFRSF11B gene—a distinct entity with a well-established role in bone metabolism and disease. There is no evidence that BTF3P11 encodes a therapeutic target or participates in known biological pathways. The inclusion of "TNFRSF11B, OPG, OCIF" as aliases for BTF3P11 is a nomenclature artifact; these names correctly belong to the osteoprotegerin gene (TNFRSF11B). Key explanation and caution: - BTF3P11 is a pseudogene and not a valid therapeutic target; the commonly listed aliases (OPG, OCIF, TNFRSF11B) refer to a completely different protein-coding gene, which is a true receptor (Osteoprotegerin, encoded by TNFRSF11B). - There is likely a confusion in databases where aliases from TNFRSF11B are incorrectly attached to BTF3P11. - For data curation and therapeutic target selection, information about osteoprotegerin/TNFRSF11B should not be attributed to BTF3P11. If you are seeking information on Osteoprotegerin (OPG/TNFRSF11B), a genuine soluble receptor with therapeutic and biomarker significance, you should refer directly to the TNFRSF11B gene and ignore the BTF3P11 pseudogene entry.

Other names

lambda h27ABTF3 homologueBRF3L1BTF3L1HUMBTFBOCIFOPGTNFRSF11B