BCL2 interacting protein 3 pseudogene 16 (BNIP3P16)

BNIP3P16 (*BCL2 interacting protein 3 pseudogene 16*, BNIP3P16) is a human **pseudogene**, meaning it is a genomic locus similar in sequence to the BNIP3 protein-coding gene but lacks the ability to encode a functional protein[1][5][6]. It has been annotated and cataloged in various genome databases but does not exhibit canonical roles such as signal transduction, receptor activity, or enzymatic function[1][5]. There is no evidence it acts as a therapeutic target—such functions are restricted to its functional paralog, *BNIP3*, which is involved in apoptosis and mitophagy[3][7]. Pseudogenes like BNIP3P16 may sometimes act as noncoding RNAs influencing related genes by competing for microRNA binding, but there is no evidence BNIP3P16 itself performs such a function in humans[2]. **Summary**: BNIP3P16 is accurately described as a pseudogene, is not a molecular target, and should not be considered a candidate receptor, enzyme, or drug-binding molecule in structured databases.

Other names

BNIP3P16BCL2/adenovirus E1B 19kDa interacting protein 3 pseudogene 16Various previous database identifiers (e.g., GC00U934800, GC19M020181, etc.)[1]HGNC: 49696NCBI Gene: 106480418Ensembl: ENSG00000267641