Target intelligence / Profile preview

Benzoyl Peroxide (BPO)

Target
BPO
Molecular classification
Organic Peroxide, Antibacterial Agent, Keratolytic Agent
01

Overview

Benzoyl peroxide is an organic peroxide compound primarily used as a topical medication for the treatment of mild to moderate acne vulgaris and, less commonly, rosacea. It acts as an antibacterial agent by generating free radicals that oxidize bacterial proteins and has mild keratolytic effects. It is available in various formulations including gels, creams, lotions, face washes, and soaps.

Other names
Dibenzoyl peroxideBenzoylperoxidePeroxide, dibenzoyl
02

Mechanism of action

Benzoyl peroxide generates free radicals that oxidize bacterial proteins—primarily targeting Cutibacterium acnes. It also has mild keratolytic effects that help remove dead skin cells and increase epithelial cell turnover.

03

Biological functions

Antimicrobial activityExfoliationOxidation of bacterial proteins
04

Disease associations

Acne vulgarisRosacea
05

Safety considerations

Skin irritationRednessDrynessPeelingAllergic contact dermatitisPhotosensitivityBleaching of hair/clothing
06

Interacting drugs

Clindamycin

1 more in the full profile.

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