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Target intelligence / Profile preview
Beta-casein A2 variant (A2 beta-casein)
- Target
- A2 beta-casein
- Molecular classification
- Casein, Phosphoprotein
01
Overview
The A2 protein most commonly refers to the A2 variant of beta-casein, a major milk protein. The primary difference between A1 and A2 beta-caseins is at amino acid position 67—proline in A2 versus histidine in A1. Some studies suggest that consuming only the A2 variant may reduce digestive discomfort compared to regular milk containing both variants.
- Other names
- A2 milk proteinA2 beta caseinA2 β-casein
02
Biological functions
Nutrient deliveryMicelle formationSource of amino acidsCalcium bindingPhosphate binding
03
Safety considerations
Potential digestive discomfort in sensitive individuals with A1 beta-casein intolerance
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