Target intelligence / Profile preview

Beta-D-galactosidase gene (lacZ)

Target
lacZ
Molecular classification
Gene, Enzyme
01

Overview

The lacZ gene encodes the enzyme beta-galactosidase, which is essential for the metabolism of lactose in bacteria by breaking it down into glucose and galactose. It is part of the lac operon, a crucial regulatory system in *Escherichia coli* that allows bacteria to adapt to lactose availability when glucose is absent[1][2][3]. The lacZ gene is often used as a reporter gene in molecular biology due to its ease of assay[5][6]. While the lacZ gene encodes an enzyme, it is not generally considered a therapeutic target in the context of human diseases but is crucial for understanding gene regulation and metabolic processes in bacteria.

Other names
lacZ genebeta-galactosidase gene
02

Mechanism of action

None applicable

03

Biological functions

Metabolism of lactoseGene regulation
04

Disease associations

Infection (indirectly through lac operon regulation in bacteria)Other (biotechnological applications)

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